One day, on her way to school, middle school student Aya suddenly falls to the ground. The doctor diagnoses her with spinocerebellar degeneration, a rare and incurable neurological disease. Entering high school, Aya's condition continues to worsen as physical movements become more difficult. Forced to attend a special boarding school, she nonetheless finds hope and happiness through the support of her new friends and family. Working hard, she completes her high school education and bravely begins a new stage in her life despite her weak health and continuous trips to the hospital. Aya never gives up, living each day of her life to the fullest until the very end. ~~ Adapted from the diary "1 Litre no Namida" (1 リットルの涙) by Kito Aya (木藤 亜也), who suffered from degenerative disease and died at the age of 25.